Reacción #2530

ord-ac9b042f4b28460bbb5f5ac06fb31c97

Ecuación de reacción

COc1ccc(N)cc1
p-anisidine
N#Cc1ccc(C(=O)O)cc1
4-cyanobenzoic acid
COc1ccc(NC(=O)c2ccc(C#N)cc2)cc1
title compound
Rendimiento 91.7%
COc1ccc(NC(=O)c2ccc(C#N)cc2)cc1
4-Cyano-N-(4-methoxyphenyl)benzamide
Rendimiento 91.7%

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Using p-anisidine (1.35 g, 11.0 mmol) and 4-cyanobenzoic acid (1.47 g, 10.0 mmol), the procedure of Reference Example 16 was repeated to obtain 2.31 g (91.7%) of the title compound in the form of colorless needle crystals.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05728835uspto-grants-1998_03