Reacción #2501394

ord-c2721fee4f024689a3357b9394133919

Disolventes

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroThe organic layer was separated
  2. 2
    Lavadowashed with 200 mL of cold water
  3. 3
    Secadodried over MgSO4
  4. 4
    Filtraciónfiltered
  5. 5
    Concentraciónconcentrated by distillation

Procedimiento

To a solution containing 1M of 2,4,6,8-tetramethylcyclotetrasiloxane and 0.01 g of (CH3CO2)2Zn was slowly added 1M of 2-hydroxyethyl acrylate. The resulting mixture was stirred for 12 hours at a room temperature. Thereafter, 200 mL of benzene and 200 mL of cold water were added. The organic layer was separated, washed with 200 mL of cold water, dried over MgSO4, filtered and concentrated by distillation to provide the title compound of Formula 1A (yield: 97%).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06811960B2uspto-grants-2004_11