Reacción #2467956

Ecuación de reacción

methyl 3-aminothiophene-2-carboxylate

sodium nitrite

dimethylamine

→

methyl 3-[(dimethylamino)diazenyl]thiophene-2-carboxylate

Condiciones de reacción

Procedimiento

Diazotization of methyl 3-aminothiophene-2-carboxylate or its precursors with sodium nitrite followed by treatment with dimethylamine provides methyl 3-[(dimethylamino)diazenyl]thiophene-2-carboxylate or its derivatives in good yield. Treatment of the above esters with ammonia gave the triazene analogs of formula (I) (3-[(dimethylamino)diazenyl]thiophene-2-carboxamide (compd No. 1), compd. No. 2, compd. No. 3, compd. No. 4, compd. No. 5).

Fuente