Reacción #2460328

Ecuación de reacción

10-(4-butylphenyl)-10H-phenothiazine

diphenyliodonium hexafluorophosphate

→

10-(4-butylphenyl)-5-phenyl-10H-phenothiazin-5-ium hexa-fluorophosphate

Disolventes

ether

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaUpon cooling to ambient temperature
2. 2
   workup.ADDITIONwas added
3. 3
   Lavadowashed with ether
4. 4
   Filtracióncollected by filtration
5. 5
   Lavadowashed three times with ether
6. 6
   OtroWithout further purification
7. 7
   Otroit was isolated in 98.2% (2.36 g)
8. 8
   Otroyield as a pale yellow solid

Procedimiento

A mixture of 10-(4-butylphenyl)-10H-phenothiazine (83) (1.44 g, 4.34 mmol), diphenyliodonium hexafluorophosphate (1.85 g, 4.34 mmol) and copper (I) benzoate (0.10 g) was heated at 120° C. for 3 hours under nitrogen. Upon cooling to ambient temperature, the mixture was transferred to a mortar-and-pestle and 50 ml of ether was added. The solid was finely powdered, washed with ether, collected by filtration and washed three times with ether. Without further purification, it was isolated in 98.2% (2.36 g) yield as a pale yellow solid.

Fuente