Reacción #2390940

Ecuación de reacción

t-butyl N-{2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-(4-hydroxyphenoxy)phenyl}-N-methylcarbamate

hydrochloric acid dioxane

→

title compound

Rendimiento 21.8%

5-{4-[6-(4-Hydroxyphenoxy)-1-methyl-1H-benzimidazol-2-ylmethoxy]benzyl}thiazolidine-2,4-dione

Rendimiento 21.8%

Condiciones de reacción

Procedimiento

Using 1.49 g of t-butyl N-{2-[4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxyacetylamino]-5-(4-hydroxyphenoxy)phenyl}-N-methylcarbamate and 10 ml of a 4N hydrochloric acid/dioxane solution, reaction and purification were carried out in a similar manner to that described in Example (2-2a), whereby 0.26 g of the title compound were obtained.

Fuente