Reacción #2383791

Ecuación de reacción

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine

→

4-Methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-ylamine

Disolventes

methanol

Pd-C

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónAfter 1 h the mixture was filtered through glass
2. 2
   Otroevaporated to an oil which

Procedimiento

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine (1.52 g, 6.0 mmol) was dissolved in methanol (100 ml) and hydrogenated at 50 psi in the presence of a catalytic quantity of 10% Pd-C. After 1 h the mixture was filtered through glass and evaporated to an oil which was used immediately in the next step.

Fuente