Reacción #2374959

Ecuación de reacción

potassium hydroxide

(E)-(R)-2-propyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)-2-buten-1-al

1,2-diaminoethane

→

(E)-(R)-2-Propyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)-2-buten-1-ol

Disolventes

isopropyl alcohol

isopropyl alcohol

Condiciones de reacción

Procedimiento

In a 100 ml stainless steel autoclave were charged 6.60 g (0.03 mol) of (E)-(R)-2-propyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)-2-buten-1-al synthesized from (1S)-α-pinene having an optical purity of 97% e.e. in a conventional manner, 28.7 mg (0.03 mmol) of RuCl2 (PPh3)3, 2.4 ml of a 0.1M 1,2-diaminoethane (0.24 mmol) solution in isopropyl alcohol, and 15 ml of a 0.1M potassium hydroxide (1.5 mmol) solution in isopropyl alcohol in a nitrogen atmosphere, and the mixture was stirred at room temperature for 3 hours under a hydrogen pressure of 50 atm.

Fuente