Reacción #2361

Ecuación de reacción

ε-caprolactone

trimethylene carbonate

propylene glycol

stannous octoate

→

ε-CAPROLACTONE TRIMETHYLENE CARBONATE

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroA flame dried
2. 2
   OtroThe flask was fitted with a flame
3. 3
   Otrodried mechanical stirrer
4. 4
   OtroThe flask was purged with nitrogen three times
5. 5
   Temperaturamaintained at this temperature for about 18-20 hours
6. 6
   OtroThe copolymer was dried under vacuum (0.1 mm Hg) at 80° C. for about 16 hours
7. 7
   Otroto remove any unreacted monomer
8. 8
   Otroat 25° C
9. 9
   Otroat room temperature

Procedimiento

A flame dried, 250 mL, round bottom single neck flask was charged with 102.7 grams (0.90 mole) of ε-caprolactone, 10.2 grams (0.10 mole) of trimethylene carbonate, 2.9 mL (40 mmol) of propylene glycol (USP), and 0.10 mL (34 μmol) of a 0.33M stannous octoate solution in toluene. The flask was fitted with a flame dried mechanical stirrer. The flask was purged with nitrogen three times before venting with nitrogen. The reaction mixture was heated to 160° C. and maintained at this temperature for about 18-20 hours. The copolymer was dried under vacuum (0.1 mm Hg) at 80° C. for about 16 hours to remove any unreacted monomer. The copolymer had an inherent viscosity of 0.25 dL/g in HFIP at 25° C. The copolymer was a viscous liquid at room temperature.

Fuente