Reacción #2358571

Ecuación de reacción

3,4-dimethoxybenzenesulfonyl chloride

triethylamine

octylamine

→

title compound

Rendimiento 78.0%

N-octyl-3,4-dimethoxybenzenesulfonamide

Rendimiento 78.0%

Disolventes

ethyl acetate

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe reaction mixture was filtered
2. 2
   Lavadothe filtrate was washed 1N HCl (2×)
3. 3
   Secadodried with MgSO4
4. 4
   Filtraciónfiltered
5. 5
   Concentraciónconcentrated in vacuo

Procedimiento

To a solution of 3,4-dimethoxybenzenesulfonyl chloride (0.750 g, 3.17 mmol), triethylamine (1.12 mL, 7.93 mmol) in 10 mL of ethyl acetate, octylamine (0.525 mL, 3.17 mmol) was added dropwise and the resulting solution was stirred overnight. The reaction mixture was filtered and the filtrate was washed 1N HCl (2×), dried with MgSO4, filtered and concentrated in vacuo to afford 0.611 g (78%) of the title compound as a white solid.

Fuente