Reacción #2358532

Ecuación de reacción

6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid

dimethylamine hydrochloride

→

3-(5-Dimethylcarbamoyl-pent-1-ynyl)-N-(2-hydroxy-1-methyl-ethyl)benzamide

Rendimiento 96.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroto obtain 8 (0.115 g, 0.363 mmol; 96% yield)

Procedimiento

6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid (4) (0.109 g, 0.377 mmol) was reacted using method C with dimethylamine hydrochloride to obtain 8 (0.115 g, 0.363 mmol; 96% yield).

Fuente