Reacción #2329030

ord-c65c8270dce34022a054ec42cb7a7cd4

Ecuación de reacción

C[C@H](N)Cc1ccccc1
d-amphetamine
CC(N)Cc1ccccc1.O=S(=O)(O)O
amphetamine sulfate
C[C@H](N)Cc1ccccc1.NCCCC[C@H](N)C(=O)O
L-lysine d-amphetamine
C[C@H](N)Cc1ccccc1
d-amphetamine
→
CS(=O)(=O)O.CS(=O)(=O)O.C[C@@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN
L-lysine-d-amphetamine Dimesylate

Reactantes

C[C@H](N)Cc1ccccc1
d-amphetamine
CC(N)Cc1ccccc1.O=S(=O)(O)O
amphetamine sulfate
C[C@H](N)Cc1ccccc1.NCCCC[C@H](N)C(=O)O
L-lysine d-amphetamine
C[C@H](N)Cc1ccccc1
d-amphetamine

Reactivos

Ninguno

Disolventes

O
water

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Male Sprague-Dawley rats were provided water ad libitum, fasted overnight, and dosed by oral gavage with 1.5, 3, 6, 12, and 60 mg/kg of amphetamine sulfate or L-lysine-d-amphetamine containing the equivalent amounts of d-amphetamine. Concentrations of d-amphetamine were measured by ELISA.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07671031B2uspto-grants-2010_03