Reacción #2329028

Ecuación de reacción

hydrochloric acid

4-t-butylphthalic anhydride

t-butylbenzene

Aluminum chloride

→

benzoic acid

Rendimiento 64.0%

4-t-butyl-2-[4-t-butylbenzoyl)benzoic acid

Rendimiento 64.0%

Disolventes

dichloroethane

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONAdded into a 500 ml three-necked flask under the environment of argon
2. 2
   workup.ADDITIONAfter the addition, they
3. 3
   OtroAfter the reaction, ice
4. 4
   workup.ADDITIONwas added gradually
5. 5
   FiltraciónAfter the precipitates were filtered
6. 6
   Lavadothey were thoroughly washed

Procedimiento

Added into a 500 ml three-necked flask under the environment of argon were 4-t-butylphthalic anhydride 36 g (176 mmole), t-butylbenzene 27 g (200 mmole) and dichloroethane 100 ml. The mixture was cooled to 0° C. Aluminum chloride 56 g (420 mmole) was added gradually to them. After the addition, they were stirred at room temperature overnight. After the reaction, ice was added gradually followed by the addition of concentrated hydrochloric acid. After the precipitates were filtered, they were thoroughly washed to give the benzoic acid substance 32 g (yield 64%, white powder).

Fuente