Reacción #2329001

ord-ef957cca0e25462c8797dd916b3c6527

Ecuación de reacción

COc1ccc2nc(-c3ccc(NCCF)nc3)oc2c1
N-(2-fluoroethyl)-5-(6-methoxy-1,3-benzoxazol-2-yl)pyridin-2-amine
COc1ccc2nc(-c3cnc(N(CCF)C(=O)OC(C)(C)C)nc3)oc2c1
tert-butyl (2-fluoroethyl)[5-(6-methoxy-1,3-benzoxazol-2-yl)pyrimidin-2-yl]carbamate
COc1ccc2nc(-c3cnc(NCCF)nc3)oc2c1
title compound
COc1ccc2nc(-c3cnc(NCCF)nc3)oc2c1
N-(2-fluoroethyl)-5-(6-methoxy-1,3-benzoxazol-2-yl)pyrimidin-2-amine

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    Otroto give 29.8 mg

Procedimiento

The title compound was synthesized from tert-butyl (2-fluoroethyl)[5-(6-methoxy-1,3-benzoxazol-2-yl)pyrimidin-2-yl]carbamate according to the procedure described for N-(2-fluoroethyl)-5-(6-methoxy-1,3-benzoxazol-2-yl)pyridin-2-amine to give 29.8 mg. MS m/z 289 (M+H).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07670591B2uspto-grants-2010_03