Reacción #2307984

ord-f2625d76c80d4caaadc3f547dd33b743

Ecuación de reacción

CC1C=CCCC1(C)C=O
triplal
O=S(=O)([O-])[O-].[Na+].[Na+]
sodium sulfate
CO
methanol
NCCO
ethanolamine
→
CC1=CC(C)C(C2NCCO2)CC1
2-(2,4-Dimethyl-cyclohex-3-enyl)-oxazolidine

Reactantes

CC1C=CCCC1(C)C=O
triplal
O=S(=O)([O-])[O-].[Na+].[Na+]
sodium sulfate
CO
methanol
NCCO
ethanolamine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    Temperaturais cooled to 0° C.
  2. 2
    Otrothe solids are removed via vacuum filtration through Celite
  3. 3
    OtroEvaporation of the solvent
  4. 4
    Otrogives a clear, slightly yellow oil

Procedimiento

To a 0° C. stirred solution of 66 g (0.47 mol) triplal and 21 g sodium sulfate in 150 mL of methanol is added 29 g (0.47 mol) of ethanolamine. The reaction is allowed to warm to room temperature. After stirring for 24 h the mixture is cooled to 0° C. and the solids are removed via vacuum filtration through Celite. Evaporation of the solvent gives a clear, slightly yellow oil.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07368415B2uspto-grants-2008_05