Reacción #2298631
ord-0a99f9f82b7e47b9a5a2b51cc9c7ed24
Ecuación de reacción
2-ethyl-4-methyl-1,6-dihydro-6-pyrimidone
4-[2-bromoethoxy]benzaldehyde
NaH
→
title compound
Rendimiento 42.0%
4-[2-[2-Ethyl-4-methyl-6-oxo-1,6-dihydro-1-pyrimidinyl]ethoxy]benzaldehyde
Rendimiento 42.0%
Reactivos
Ninguno
Condiciones de reacción
Condiciones detalladas
See reaction.notes.procedure_details.
Procedimiento
The title compound (1.7 g, 42%) was prepared from 2-ethyl-4-methyl-1,6-dihydro-6-pyrimidone (2.0 g, 14.49 mmol), 4-[2-bromoethoxy]benzaldehyde (332 g, 14.19 mmol). LIBr (2.9 g, 33.33 mmol) and NaH (0.45 g, 18.84 mmol) as base, by a similar procedure to that described in preparation 1.