Reacción #2275731

Ecuación de reacción

N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide

5-bromo-1-(4-oxo-cyclohexyl)-1H-pyrimidin-2-one

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title compounds

N-({1-[4-(5-Bromo-2-oxo-2H-pyrimidin-1-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

Condiciones de reacción

Procedimiento

The title compounds were prepared as white solids from the reductive amination of 5-bromo-1-(4-oxo-cyclohexyl)-1H-pyrimidin-2-one (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in Example 2 Step C) using the procedure described in Step D of Example 1.

Fuente