Reacción #2198103

Ecuación de reacción

tert.butyl N(3-amino-3-thioxopropyl)carbamate

1-bromo-2-butanone

→

2-(4-ethyl-thiazol-2-yl)-ethylamine hydrobromide

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe reaction mixture is evaporated down
2. 2
   Otrothe residue is purified by chromatography

Procedimiento

2.00 g (9.50 mmol) tert.butyl N(3-amino-3-thioxopropyl)carbamate and 1.58 g (10.45 mmol) 1-bromo-2-butanone are refluxed in 40 ml of ethanol for 16 hours with stirring. The reaction mixture is evaporated down, the residue is purified by chromatography.

Fuente