Reacción #2195498

Ecuación de reacción

product

Diethyl 3,3-difluoropentanedioate

benzylamine

→

title compound

1-Benzyl-4,4-difluoropiperidine-2,6-dione

Condiciones de reacción

Tratamiento posterior

1. 1
   Otropurify by silica gel chromatography

Procedimiento

React an 8.1 mmol portion of the product of Example 14 with benzylamine using the general procedure set forth in Example 8, and purify by silica gel chromatography using ethyl acetate/hexane as eluant to yield the title compound.

Fuente