Reacción #2168677

ord-0eb2698c0d9b427c98860b8dca9e45c2

Ecuación de reacción

CN1CCCCC1CO
1-methyl-2-piperidinemethanol
COS(=O)(=O)c1ccc(C)cc1
methyl p-toluenesulfonate
→
C[N+]1(C)CCCCC1CO.Cc1ccc(S(=O)(=O)[O-])cc1
desired compound
Rendimiento 157.1%
C[N+]1(C)CCCCC1CO.Cc1ccc(S(=O)(=O)[O-])cc1
1,1-Dimethyl-2-hydroxymethylpiperidinium p-toluenesulfonate
Rendimiento 157.1%

Reactantes

CN1CCCCC1CO
1-methyl-2-piperidinemethanol
COS(=O)(=O)c1ccc(C)cc1
methyl p-toluenesulfonate

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The procedures of Reference Example 3 were repeated using 2.58 g of 1-methyl-2-piperidinemethanol and 3.72 g of methyl p-toluenesulfonate to give 4.95 g of the desired compound.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05183811uspto-grants-1993_02