Reacción #216578

ord-0d91570a371248f4a23fcce6f0f6420d

Ecuación de reacción

COC(=O)[C@@H](N)C(C)C
valine methyl ester
O=C(Cl)CCCCCl
5-chloropentanoyl chloride
→
COC(=O)[C@@H](NC(=O)CCCCCl)C(C)C
N-(5-chloropentanoyl)valine methyl ester

Reactantes

COC(=O)[C@@H](N)C(C)C
valine methyl ester
O=C(Cl)CCCCCl
5-chloropentanoyl chloride

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Using the method of Example 1, Step A, valine methyl ester and 5-chloropentanoyl chloride were coupled to provide N-(5-chloropentanoyl)valine methyl ester.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05468733uspto-grants-1995_11