Reacción #216332

Ecuación de reacción

(1S)-1-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol

1-[4-(2,2,3,3,3-pentafluoropropoxy)phenyl]-2(1H,3H)-imidazolone

→

1-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3-[4-(2,2,3,3,3-pentafluoropropoxy)phenyl]-2(1H,3H)-imidazolone

Rendimiento 22.0%

Condiciones de reacción

Procedimiento

In the same manner as in Reference Example 5, starting from 1.0 g of (1S)-1-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol and 1.23 g of 1-[4-(2,2,3,3,3-pentafluoropropoxy)phenyl]-2(1H,3H)-imidazolone, 0.43 g of 1-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3-[4-(2,2,3,3,3-pentafluoropropoxy)phenyl]-2(1H,3H)-imidazolone was obtained as colorless plates.

Fuente