Reacción #2161239

Ecuación de reacción

4-tert-butoxyphenyldiphenylsulfonium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate

Methanesulfonic acid

→

(4-hydroxyphenyl)diphenylsulfonium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate

Disolventes

dichloromethane

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroprepared in Synthesis Example 14
2. 2
   Temperaturawas heated
3. 3
   LavadoThe organic layer was washed with 30 g of water three times
4. 4
   Concentraciónconcentrated
5. 5
   workup.ADDITIONDiethyl ether was added to the
6. 6
   Concentraciónconcentrate for crystallization
7. 7
   FiltraciónThe crystals were filtered
8. 8
   Otrodried
9. 9
   Otroobtaining the target compound in an amount of 4.9 g

Procedimiento

In 60 g of dichloromethane was dissolved 6.7 g of 4-tert-butoxyphenyldiphenylsulfonium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate (PAG4) prepared in Synthesis Example 14. Methanesulfonic acid, 0.1 g, was added to the solution, which was heated and stirred at 40° C. for 3 hours. The organic layer was washed with 30 g of water three times, and concentrated. Diethyl ether was added to the concentrate for crystallization. The crystals were filtered and dried, obtaining the target compound in an amount of 4.9 g.

Fuente