Reacción #216076

Ecuación de reacción

Octadecylamine

Glycidol

→

white solid

Rendimiento 95.9%

3-Octadecylamino-1,2-Dihydroxy-Propane

Rendimiento 95.9%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaunder reflux for one additional hour
2. 2
   Temperaturacooled to room temperature
3. 3
   Otroevaporated to dryness

Procedimiento

Octadecylamine (18 g) was dissolved in 200 ml methanol and heated to 60° C. Glycidol (4.95 g) was added dropwise under constant stirring over one and half hours. The reaction mixture was kept under reflux for one additional hour, and then cooled to room temperature, and evaporated to dryness, resulting in 22 g white solid material. This was then recrystallized from hexane, to yield ODP, mp 81°-83° C.

Fuente