Reacción #215767

Ecuación de reacción

2-Methoxy-4-(1-acetyl-4-piperidyloxy)benzoic acid

thionyl chloride

→

2-methoxy-4-(1-acetyl-4-piperidyloxy)benzoyl chloride

Disolventes

THF

Condiciones de reacción

Tratamiento posterior

1. 1
   Concentraciónconcentrated in vacuo

Procedimiento

2-Methoxy-4-(1-acetyl-4-piperidyloxy)benzoic acid (0.546 g, 1.86 mmol) in THF (10 ml) was stirred under nitrogen and treated with thionyl chloride (0.27 ml, 0.44 g, 3.7 mmol). The mixture was stirred at ambient temperature for 18 hours, then concentrated in vacuo to give 2-methoxy-4-(1-acetyl-4-piperidyloxy)benzoyl chloride.

Fuente