Reacción #214615

Ecuación de reacción

6,7-dibromo-8-nitro-1,4-benzodioxane-5-carboxylic acid

thionyl chloride

→

6,7-dibromo-8-nitro-1,4-benzodioxane-5-carbonyl chloride

Rendimiento 91.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroprovided with an agitator
2. 2
   TemperaturaThe mixture was heated
3. 3
   Temperaturaunder reflux
4. 4
   Otrothe excess thionyl chloride was removed under vacuum
5. 5
   workup.DISSOLUTIONThe residue was dissolved in 100 ml of isopropyl ether
6. 6
   Otrothe solvent removed
7. 7
   Otrothe produced air-dried

Procedimiento

96 g of 6,7-dibromo-8-nitro-1,4-benzodioxane-5-carboxylic acid and 200 ml of thionyl chloride were introduced into a balloon flask provided with an agitator and a thermometer. The mixture was heated under reflux and then the excess thionyl chloride was removed under vacuum. The residue was dissolved in 100 ml of isopropyl ether and then the solvent removed and the produced air-dried. 91 g of 6,7-dibromo-8-nitro-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 215° C.; yield: 91%).

Fuente