Reacción #214066

Ecuación de reacción

1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-3,3-dimethyl-4-chloro-butan-2-ol

acetic anhydride

→

1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-2-acetoxy-3,3-dimethyl-4-chloro-butane

Rendimiento 65.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   ConcentraciónThereafter, it was concentrated
2. 2
   workup.DISTILLATIONby distilling off excess acetic anhydride in vacuo
3. 3
   Otroto crystallize out at 0° C

Procedimiento

23.1 g (0.07 mol) of 1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-3,3-dimethyl-4-chloro-butan-2-ol were dissolved in 100 ml of acetic anhydride and the solution was heated to 100° C. for 12 hours. Thereafter, it was concentrated by distilling off excess acetic anhydride in vacuo. The oil which remained was taken up in 150 ml of diisopropyl ether and the product was allowed to crystallize out at 0° C. 17 g (65% of theory) of 1-(4-chlorophenoxy)-1-(1,2,4-triazol-1-yl)-2-acetoxy-3,3-dimethyl-4-chloro-butane of melting point 111°-117° were obtained.

Fuente