Reacción #2122518

Ecuación de reacción

Compound 20

N,N-dihexyl-2-methylbenzo[d]thiazole-6-sulfonamide

p-toluenesulfonic acid methyl ester

hexane

→

Compound 21

Rendimiento 78.9%

6-(N,N-dihexylsulfamoyl)-2,3-dimethylbenzo[d]-thiazole-3-ium tosylate

Rendimiento 78.9%

Disolventes

ethyl acetate

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturato cool to room temperature
2. 2
   OtroA sticky dark brown solid separated which
3. 3
   Lavadowas washed with hexane
4. 4
   Otrodried under vacuum

Procedimiento

A mixture of Compound 20 (2.0 g, 5.0 mmol) and p-toluenesulfonic acid methyl ester (1.4 g, 7.5 mmol) was heated in a pressure tube at 130° C. for 2 hours. The mixture was allowed to cool to room temperature, and the resulting mass was dissolved in ethyl acetate (4 ml). The combined mixture was then added drop wise to hexane (40 ml). A sticky dark brown solid separated which was washed with hexane and dried under vacuum to yield 2.3 g (78%) of Compound 21 which was used without any further purification. The structure of this compound is given below:

Fuente