Reacción #2072153

Ecuación de reacción

6-Bromo-naphthalene-2-carbonyl chloride

(7-amino-1,2,3,4-tetrahydro-quinolin-3-yl)-methanol

→

title compound

6-Bromo-naphthalene-2-carboxylic acid (3-hydroxymethyl-1,2,3,4-tetrahydro-quinolin-7-yl)-amide

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThis material was prepared analogous to the procedure
2. 2
   Otroprepared

Procedimiento

This material was prepared analogous to the procedure described for Example 1(c). 6-Bromo-naphthalene-2-carbonyl chloride, Example 2(a), (258 mg, 0.96 mmol) reacted with (7-amino-1,2,3,4-tetrahydro-quinolin-3-yl)-methanol (171 mg, 0.96 mmol, prepared according to the procedure described in WO03049702) to give the title compound as an light-brown amorphous solid. MS (ESI, pos. ion) m/z: 413 (M+1).

Fuente