Reacción #2069924

Ecuación de reacción

Acetic anhydride

4-isopropylaniline

→

N-Acetyl-4-isopropylaniline

Disolventes

chloroform

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaIn the course of this, intense heating of the reaction mixture
2. 2
   workup.ADDITIONOn completion of the dropwise addition
3. 3
   ConcentraciónThe reaction mixture is concentrated to dryness
4. 4
   Otrothe resulting, reddish-white solid is recrystallized from hexane

Procedimiento

Acetic anhydride (26.0 g, 254 mmol) is slowly added dropwise to a solution of 4-isopropylaniline (17.2 g, 127 mmol) in 80 ml of chloroform. In the course of this, intense heating of the reaction mixture occurs. On completion of the dropwise addition, the mixture is stirred at room temperature for another 2 h. The reaction mixture is concentrated to dryness and the resulting, reddish-white solid is recrystallized from hexane.

Fuente