Reacción #2063054

Ecuación de reacción

phthalic anhydride

methylamine

→

N-methylphthalimide

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaThe mixture was heated
2. 2
   Temperaturaat reflux for four hours
3. 3
   Otroafter which approximately 50 ml of the aqueous amine was removed by distillation
4. 4
   Temperaturato cool
5. 5
   FiltraciónThe resultant precipitate was collected by filtration

Procedimiento

To a suspension of 25.0 g (0.17 mol) of phthalic anhydride in 200 ml of water was added 30 g (0.38 mol) of a 40% aqueous solution of methylamine. The mixture was heated at reflux for four hours, after which approximately 50 ml of the aqueous amine was removed by distillation and the mixture allowed to cool. The resultant precipitate was collected by filtration to yield 10.3 g of N-methylphthalimide (cyclic imide (b)(4)).

Fuente