Reacción #2045916

ord-2a5bee964a154fec84b67fdf575ca594

Ecuación de reacción

CCCCCCCCOC(=O)Nc1ccc(S(=O)(=O)N[C@H](CC(=O)OCc2ccccc2)CN(C)C)cc1
(R)-benzyl 4-(dimethylamino)-3-(4-(octyloxycarbonylamino)phenylsulfonamido)butanoate
CI
methyl iodide
→
CCCCCCCCOC(=O)Nc1ccc(S(=O)(=O)N[C@H](CC(=O)OCc2ccccc2)C[N+](C)(C)C)cc1.[I-]
title compound
CCCCCCCCOC(=O)Nc1ccc(S(=O)(=O)N[C@H](CC(=O)OCc2ccccc2)C[N+](C)(C)C)cc1.[I-]
(R)-4-(benzyloxy)-N,N,N-trimethyl-2-(4-(octyloxycarbonylamino)phenyl-sulfonamido)-4-oxobutan-1-aminium iodide

Reactantes

CCCCCCCCOC(=O)Nc1ccc(S(=O)(=O)N[C@H](CC(=O)OCc2ccccc2)CN(C)C)cc1
(R)-benzyl 4-(dimethylamino)-3-(4-(octyloxycarbonylamino)phenylsulfonamido)butanoate
CI
methyl iodide

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

According to the method described in example S72b, (R)-benzyl 4-(dimethylamino)-3-(4-(octyloxycarbonylamino)phenylsulfonamido)butanoate was reacted with methyl iodide to give the title compound as a white solid in quantitative yield. MS ESI 563.3 [M]+, calcd for [C29H44N3O6S+] 562.74

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08410150B2uspto-grants-2013_04