Reacción #2016150

Ecuación de reacción

9-phenylanthracene

bromine

sodium thiosulfate

→

9-bromo-10-phenylanthracene

Disolventes

toluene

carbon tetrachloride

carbon tetrachloride

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONwas dropped in the reaction solution at the room temperature
2. 2
   workup.STIRRINGthe solution was further stirred for 1 hour
3. 3
   LavadoAn organic layer of the reaction mixture was washed with aqueous sodium hydroxide (2.0 mol/L) and saturated saline
4. 4
   Secadodried with magnesium sulfate
5. 5
   FiltraciónThis mixture was filtrated naturally
6. 6
   Otrocondensed
7. 7
   Otroto obtain a solid
8. 8
   Filtraciónthe solution was subjected to suction filtration through Florisil, celite
9. 9
   ConcentraciónThe filtrate was concentrated
10. 10
    Otroto obtain a solid
11. 11
    Otrothe solid was recrystallized with a mixture solution of dichloromethane and hexane, whereby 27.8 g of a light yellow powdery solid
12. 12
    Otrowas obtained with the yield of 85%

Procedimiento

25.0 g (98.3 mmol) of 9-phenylanthracene was put into a 1-L three-neck flask, and 300 mL of carbon tetrachloride was added thereto. A solution in which 15.6 g (98.3 mmol) of bromine was dissolved in 40 mL of carbon tetrachloride was dropped in the reaction solution at the room temperature. After the dropping, the reaction solution was stirred at the room temperature for 1 hour. Thereafter, the reaction is completed by adding a sodium thiosulfate aqueous solution, and the solution was further stirred for 1 hour. An organic layer of the reaction mixture was washed with aqueous sodium hydroxide (2.0 mol/L) and saturated saline and dried with magnesium sulfate. This mixture was filtrated naturally, and the filtrate was condensed to obtain a solid. The solid was dissolved in toluene, and the solution was subjected to suction filtration through Florisil, celite, and then alumina. The filtrate was concentrated to obtain a solid, and the solid was recrystallized with a mixture solution of dichloromethane and hexane, whereby 27.8 g of a light yellow powdery solid that was a target matter was obtained with the yield of 85%.

Fuente