Reacción #1985943

Ecuación de reacción

methyl 5-acetoxy-2-formyl-4-methoxycinnamate

→

desired product

Methyl 5-Acetoxy-2-formyl-4-methoxyhydrocinnamate

Disolventes

ethyl acetate

Condiciones de reacción

Tratamiento posterior

1. 1
   Filtraciónfiltered
2. 2
   ConcentraciónThe filtrate is concentrated in vacuo
3. 3
   Otrothe residue purified by HPLC
4. 4
   Lavadoeluting 50% ethyl acetate in hexanes

Procedimiento

A mixture of methyl 5-acetoxy-2-formyl-4-methoxycinnamate (10.8 g) and 10% palladium on carbon (3 g) in ethyl acetate (100 ml) is hydrogenated at 45 psi for about 18 hours and filtered. The filtrate is concentrated in vacuo and the residue purified by HPLC, eluting 50% ethyl acetate in hexanes, to give the desired product.

Fuente