Reacción #1985940

Ecuación de reacción

vanillin

triethylamine

acetic anhydride

→

desired product

4-Acetoxy-3-methoxybenzaldehyde

Disolventes

ether

methylene chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   Lavadothe solution washed with water, brine
2. 2
   Secadodried over magnesium sulfate
3. 3
   Filtraciónfiltered
4. 4
   Concentraciónconcentrated in vacuo

Procedimiento

A solution of vanillin (60.8 g), triethylamine (60 ml), acetic anhydride (44 ml), and 4-dimethylaminopyridine (1.0 g) in methylene chloride (800 ml) is stirred at room temperature for about 30 minues, and the volume then reduced by 50% in vacuo. The residue is diluted with ether and the solution washed with water, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.

Fuente