Reacción #1973965

Ecuación de reacción

4-chloro-3-nitroaniline

methanesulfonyl chloride

pyridine

→

title compound

Rendimiento 92.2%

N-(4-chloro-3-nitrophenyl)methanesulfonamide

Rendimiento 92.2%

Disolventes

THF

HCl

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe resulting precipitate was filtered
2. 2
   Otroair-dried

Procedimiento

A mixture of 4-chloro-3-nitroaniline (5.0 g, 29 mmol), methanesulfonyl chloride (2.37 mL, 30.4 mmol) and pyridine (5.9 mL, 72.4 mmol) in THF (100 mL) was stirred for 24 h. Poured in 1M HCl (500 mL). The resulting precipitate was filtered and air-dried to provide the title compound as a solid (6.7 g, 92%).

Fuente