Reacción #1973928

ord-2c5e79c602a84d9fa0caec80d5c30337

Ecuación de reacción

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid
→
O=C(O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)O
2-(12-phthalimido dodecyl)propane dioic acid
Rendimiento 100.0%

Reactantes

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid

Reactivos

Ninguno

Disolventes

ClCCl
dichloromethane

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Following general procedure D, 16.0 mmol (8.45 g) of 5c and 160 mmol (11.9 mL) of trifluoroacetic acid were reacted in 12 mL of dichloromethane at room temperature and the mixture was processed. Yield 100%.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08501199B2uspto-grants-2013_08