Reacción #1957253

ord-ef76600b6f3440a9a463417d54c86752

Ecuación de reacción

CCN(CC)C(=O)c1cc(OC)cc(OC)c1
N,N-diethyl-3,5-dimethoxybenzamide
C=C(C)CBr
3-bromo-2-methylpropene
CC(C)CSC[C@H]1O[C@@H](n2cnc3c(=O)nc[nH]c32)[C@H](O)[C@@H]1O
Sibi
→
COc1cc(OC)c2cc(C)cc(O)c2c1
5,7-Dimethoxy-3-methyl-1-naphthol
Rendimiento 50.0%

Reactantes

CCN(CC)C(=O)c1cc(OC)cc(OC)c1
N,N-diethyl-3,5-dimethoxybenzamide
C=C(C)CBr
3-bromo-2-methylpropene
CC(C)CSC[C@H]1O[C@@H](n2cnc3c(=O)nc[nH]c32)[C@H](O)[C@@H]1O
Sibi

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

5,7-Dimethoxy-3-methyl-1-naphthol is synthesized from N,N-diethyl-3,5-dimethoxybenzamide and 3-bromo-2-methylpropene according to the method described by Sibi et al. (J. Org. Chem. 1986, Vol. 51, pp. 271-273). The yield is approximately 50%.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06096246uspto-grants-2000_08