Reacción #1929032

ord-694bff5dd88b45c78e7ec4c0d298228d

Ecuación de reacción

O.O.[Na+].[Na+].[O]=[Cr](=[O])([O-])[O][Cr](=[O])(=[O])[O-]
sodium dichromate dihydrate
CCOCC
ether
CCCCCCCCCCC(O)CBr
1-bromo-2-dodecanol
→
CCCCCCCCCCC(=O)CBr
1-bromo-2-dodecanone
Rendimiento 80.0%

Reactantes

O.O.[Na+].[Na+].[O]=[Cr](=[O])([O-])[O][Cr](=[O])(=[O])[O-]
sodium dichromate dihydrate
CCOCC
ether
CCCCCCCCCCC(O)CBr
1-bromo-2-dodecanol

Reactivos

Ninguno

Disolventes

O
water
O=S(=O)(O)O
sulfuric acid
CC(C)=O
acetone

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroA solution obtained in advance
  2. 2
    workup.ADDITIONwas dropped
  3. 3
    Otrothe solvent was removed
  4. 4
    OtroAs a result, a white solid was obtained

Procedimiento

In a 1000 ml eggplant-shaped flask, 14 g of 1-bromo-2-dodecanol was dissolved in 110 ml of acetone. A solution obtained in advance by dissolving 35 g of sodium dichromate dihydrate in 150 ml of distilled water and 25 ml of sulfuric acid was dropped thereto. These substances were stirred at room temperature for 1.5 hours, and then 250 ml of ether was added thereto. The resultant substance was dehydrated, and the solvent was removed. As a result, a white solid was obtained. The yield was 80%.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08945769B2uspto-grants-2015_02