Reacción #1916766

ord-96ae0b07bc734da89cfdb7ace9c87de3

Ecuación de reacción

O=C(Cl)C12CC3CC(O)(C1)CC(C(=O)Cl)(C3)C2
1,3-dichloroformyl-5-hydroxyadamantane
CN(C)C
trimethylamine
C[Si](C)(C)Cl
trimethylsilyl chloride
→
C[Si](C)(C)OC12CC3CC(C(=O)Cl)(C1)CC(C(=O)Cl)(C3)C2
1,3-dichloroformyl-5-trimethylsiloxyadamantane

Reactantes

O=C(Cl)C12CC3CC(O)(C1)CC(C(=O)Cl)(C3)C2
1,3-dichloroformyl-5-hydroxyadamantane
CN(C)C
trimethylamine
C[Si](C)(C)Cl
trimethylsilyl chloride

Reactivos

Ninguno

Disolventes

ClCCl
methylene chloride

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroReaction
  2. 2
    Otrowas carried out at room temperature

Procedimiento

The 1,3-dichloroformyl-5-hydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature to obtain 1,3-dichloroformyl-5-trimethylsiloxyadamantane.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07063932B2uspto-grants-2006_06