Reacción #1876820

Ecuación de reacción

1,3,5-trihydroxyadamantane

trimethylamine

trimethylsilyl chloride

→

1,3-dihydroxy-5-trimethylsiloxyadamantane

Disolventes

methylene chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroReaction
2. 2
   Otrowas carried out at room temperature
3. 3
   OtroThe reaction product was partitioned by high performance liquid chromatography

Procedimiento

This 1,3,5-trihydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature. The reaction product was partitioned by high performance liquid chromatography to obtain 1,3-dihydroxy-5-trimethylsiloxyadamantane.

Fuente