Reacción #1870447

ord-869d5d2e367a4478bd6388917c4fbdfe

Ecuación de reacción

OB(O)c1cccs1
2-thiopheneboronic acid
COC(=O)c1cc(C)cc(Br)c1
methyl 3-bromo-5-methylbenzoate
→
COC(=O)c1cc(C)cc(-c2ccsc2)c1
methyl 3-methyl-5-(3-thienyl)benzoate

Reactantes

OB(O)c1cccs1
2-thiopheneboronic acid
COC(=O)c1cc(C)cc(Br)c1
methyl 3-bromo-5-methylbenzoate

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Following the general procedure of EXAMPLE 766 and making non-critical variations but using 2-thiopheneboronic acid and methyl 3-bromo-5-methylbenzoate, methyl 3-methyl-5-(3-thienyl)benzoate is obtained.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07498436B2uspto-grants-2009_03