Reacción #1869149

ord-f4736c1983ad4437920881e9356b17a0

Ecuación de reacción

C=CCCCCCCCCC(=O)O
10-undecenoic acid
O=C(Cl)C(=O)Cl
(COCl)2
C=CCCCCCCCCC(=O)Cl
10-undecenoyl chloride
Rendimiento 100.0%

Reactivos

Ninguno

Disolventes

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroThe solvent was removed under reduced pressure

Procedimiento

To a stirred solution of 10-undecenoic acid (5.055 mL, 25 mmol) in CH2Cl2 (50 mL) was slowly added (COCl)2 (4.364 mL, 50 mmol). The mixture was stirred at room temperature overnight. The solvent was removed under reduced pressure to give 10-undecenoyl chloride (25 mmol). The product was used for the next reaction without further purification. 1H NMR (500 MHz, CDCl3) δ 1.29-1.48 (m, 10H), 1.71 (m, 2H), 2.05 (m, 2H), 2.88 (t, J=7 Hz, 2H), 4.98 (m, 2H), 5.80 (m, 1H).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07498292B2uspto-grants-2009_03