Reacción #1860251

ord-44bf66ef594b407a81f50752d8f3c178

Ecuación de reacción

COc1cc(O)c(C(=O)O)cc1C12CC3CC(CC(C3)C1)C2
5-adamantan-1-yl-2-hydroxy-4-methoxybenzoic acid
NCc1ccc(O)c(O)c1
3,4-dihydroxybenzylamine
COc1cc(O)c(C(=O)NCc2ccc(O)c(O)c2)cc1C12CC3CC(CC(C3)C1)C2
5-adamantan-1-yl-N-(3,4-dihydroxybenzyl)-2-hydroxy-4-methoxybenzamide

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

0.17 g of the target compound is obtained as white solid in substantially the same manner as in (2) of Example 1, except for using 5-adamantan-1-yl-2-hydroxy-4-methoxybenzoic acid instead of 5-adamantan-1-yl-2,4-dihydroxybenzoic acid and using 3,4-dihydroxybenzylamine instead of dopamine.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09254251B2uspto-grants-2016_02