Reacción #1847720
ord-156b5646cd3b40188857c28bbd8d31cc
Ecuación de reacción
4-chloro-2-(4-chlorophenyl)-6-isopropylpyrimidine
morpholine
→
2-(4-Chlorophenyl)-6-isopropyl-4-morpholinopyrimidine
Reactivos
Ninguno
Disolventes
Condiciones de reacción
Temperatura
130°CELSIUS
Condiciones detalladas
See reaction.notes.procedure_details.
Tratamiento posterior
- 1TemperaturaAfter cooling
- 2Filtraciónthe solid was filtered off with suction
- 3Otrodried at 50° C. in vacuo
Procedimiento
A mixture of 267 mg of 4-chloro-2-(4-chlorophenyl)-6-isopropylpyrimidine and 522 mg of morpholine was heated at 130° C. for 2 hours. After cooling, 20 ml of water were added, the mixture was stirred, and the solid was filtered off with suction and dried at 50° C. in vacuo. Yield: 0.28 g.