Reacción #1824338
ord-52acfb1f88a44f609e931ae1d08f361a
Ecuación de reacción
pyrrolidine
lawsone
THF
p-toluenesulphonic acid
lawsone
→
title compound
2-(5,5-dimethylhex-1-enyl)-3-hydroxy-naphthalene-1,4-dione
Reactivos
Ninguno
Disolventes
Condiciones de reacción
Condiciones detalladas
See reaction.notes.procedure_details.
Procedimiento
The aldehyde (8.46 mmol) was coupled to lawsone following the procedure set out in Example 42 using lawsone (1.18 g),THF (20 ml), pyrrolidine (672 μl), benzene (40 ml) and p-toluenesulphonic acid (1.95 g). 391 mg of the title compound was isolated after purification.