Reacción #1818820

ord-3aab29452de44565a0a6efc7ec9ce0f2

Ecuación de reacción

O=C(O)c1ccc2c(c1)Sc1ccc3c(c1CC2)C(=O)CC3
1-oxo-2,3,11,12-tetrahydro-1H-benzo[b]indeno[4,5-f]-thiepin-8-carboxylic acid
O=C(O)C1=CC2=CCCC=C2Sc2c1ccc1c2C(=O)CC1
1-oxo-2,3,9,10-tetrahydro-1H-benzo[b]indeno[5,4-f]thiepin-6-carboxylic acid
→
O=C(O)c1ccc2c(c1)Sc1ccc3c(c1CC2)C(O)CC3
title compound
O=C(O)c1ccc2c(c1)Sc1ccc3c(c1CC2)C(O)CC3
(±)-1-Hydroxy-2,3,11,12-tetrahydro-1H-benzo[b]indeno-[4,5-f]thiepin-8-carboxylic acid

Reactantes

O=C(O)c1ccc2c(c1)Sc1ccc3c(c1CC2)C(=O)CC3
1-oxo-2,3,11,12-tetrahydro-1H-benzo[b]indeno[4,5-f]-thiepin-8-carboxylic acid
O=C(O)C1=CC2=CCCC=C2Sc2c1ccc1c2C(=O)CC1
1-oxo-2,3,9,10-tetrahydro-1H-benzo[b]indeno[5,4-f]thiepin-6-carboxylic acid

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Substituting an equivalent amount of 1-oxo-2,3,11,12-tetrahydro-1H-benzo[b]indeno[4,5-f]-thiepin-8-carboxylic acid in Example 32 for 1-oxo-2,3,9,10-tetrahydro-1H-benzo[b]indeno[5,4-f]thiepin-6-carboxylic acid provided the title compound.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04622403uspto-grants-1986_11