Reacción #1797529

ord-a1b75f566ccc4802ab7a0ef5d1b0449e

Ecuación de reacción

O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
Intermediate 3
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
CC1CCCN1
2-methylpyrrolidine
→
CC1CCCN1c1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccccc1
5-(2-Methyl-pyrrolidin- 1-y1)-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

Reactantes

O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
Intermediate 3
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
CC1CCCN1
2-methylpyrrolidine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

5-(2-Methyl-pyrrolidin- 1-y1)-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and 2-methylpyrrolidine. Mass spectrum (ES) MH+=405.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07790711B2uspto-grants-2010_09