Reacción #1771992

Ecuación de reacción

N-tertbutoxycarbonyl-4-allyl-4-methylproline

→

N-tert-butoxycarbonyl 4-propyl-4-methylproline

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe mixture was filtered
2. 2
   Concentraciónconcentrated

Procedimiento

A solution of N-tertbutoxycarbonyl-4-allyl-4-methylproline (400 mg, 1.48 mmol) (see Example II Step 4) and 10% Pd on carbon (400 mg) in methanol (20 mL) was hydrogenated at 50 psi for 4 hours. The mixture was filtered and concentrated.

Fuente