Reacción #1771990

ord-56238b79bf8e4876a8c816dff94dc2f6

Ecuación de reacción

CC1(C)CN(C(=O)OC(C)(C)C)[C@@](C(=O)O)(C(C)(C)C)C1
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline
CC1(C)CN[C@H](C(=O)O)C1
4,4-Dimethylproline

Disolventes

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    ConcentraciónThe solution was concentrated
  2. 2
    Otrodried under high vacuum
  3. 3
    Otrotaken to the next step without further purification

Procedimiento

A solution of tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline in dichloromethane (5 mL) and trifluoroacetic (5 mL) was stirred at room temperature for five hours. The solution was concentrated, dried under high vacuum and taken to the next step without further purification.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: USRE043298E1uspto-grants-2012_04