Reacción #1750

ord-7f6c0cb8ddf545bda5b486eb8435608e

Ecuación de reacción

CN(C)Cc1ccc([C@H]2CC[C@H](O)CC2)cc1
trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol
CCN(CC)CC.O=C(Cl)C1CC1
cyclopropane carboxylic acid chloride triethylamine
→
CN(C)Cc1ccc([C@H]2CC[C@H](OC(=O)C3CC3)CC2)cc1
trans-O-cyclopropanoyl-4-(4-dimethylaminomethylphenyl)-cyclohexanol

Reactantes

CN(C)Cc1ccc([C@H]2CC[C@H](O)CC2)cc1
trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol
CCN(CC)CC.O=C(Cl)C1CC1
cyclopropane carboxylic acid chloride triethylamine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

from trans-4-(4-dimethylaminomethylphenyl)-cyclohexanol and cyclopropane carboxylic acid chloride/triethylamine. Colourless wax.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05726205uspto-grants-1998_03